# Scientific American

Type: Company

Source: Legal & RegTech Intelligence Brief — https://getlegalbrief.com/entity/scientific-american
Canonical HTML page: https://getlegalbrief.com/entity/scientific-american

## Timeline

- **2026-03**: Current Status — Regulatory bodies and industry leaders report a significant decline in animal-based IND applications.
- **2024**: Industry Pivot — Major pharma firms like AstraZeneca and Sanofi increase investment in human-on-a-chip technologies.
- **2022-12**: FDA Modernization Act 2.0 — President Biden signs legislation ending the animal testing mandate.
- **1938**: FD&C Act Passed — Federal Food, Drug, and Cosmetic Act mandates animal testing for all new drugs.

## Recent coverage (1 stories)

### Regulatory Shift: The Decline of Animal Testing in Drug Development
2026-03-08 18:25:15 · Sentiment: Positive · Impact: 7/10 · Sources: 2

The pharmaceutical industry is undergoing a historic shift as the FDA Modernization Act 2.0 ends the decades-long mandate for animal testing. This transition toward New Approach Methodologies (NAMs) like organ-on-a-chip and AI modeling is redefining the legal and regulatory requirements for drug safety validation.
Full story: https://getlegalbrief.com/story/regulatory-shift-animal-testing-decline-drug-development

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